Comfort Inn Hyannis - Cape Cod: address, phone and airport distance

Comfort Inn Hyannis - Cape Cod, a Comfort Inn hotel (Choice Hotels) in Barnstable, United States. Address: 259 Main Street, Hyannis, MA, 02601.

Comfort Inn Hyannis - Cape Cod is a Comfort Inn hotel (Choice Hotels) at 259 Main Street, Hyannis, MA, 02601, United States. The nearest airport with scheduled flights is Cape Cod Gateway Airport (HYA), 1.7 km away in a straight line.

From Choice Hotels's own hotel listing, collected 20 Sep, 2026.

Comfort Inn Hyannis - Cape Cod: quick facts

Brand: Comfort Inn (Choice Hotels)
Address: 259 Main Street, Hyannis, MA, 02601
City: Barnstable, Massachusetts, United States
Map: 41.65393, -70.27982

Check live rates for Comfort Inn Hyannis - Cape Cod

Nearest airports

Airport	Straight-line distance
Cape Cod Gateway Airport (HYA)	1.7 km
Nantucket Memorial Airport (ACK)	48.2 km
New Bedford Regional Airport (EWB)	56.3 km

Calculated from map positions; the road route is longer.

Other Choice Hotels hotels in Barnstable

Econo Lodge West Yarmouth on Cape Cod
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Hotels from other chains nearby

Americas Best Value Inn & Suites Hyannis Cape Cod (Sonesta), 221 m away
DoubleTree by Hilton Hotel Cape Cod - Hyannis (Hilton), 803 m away
Hampton Inn & Suites Cape Cod-West Yarmouth (Hilton), 1.4 km away
Courtyard by Marriott Cape Cod Hyannis (Marriott International), 1.9 km away
Fairfield by Marriott Inn & Suites Cape Cod Hyannis (Marriott International), 2.3 km away
Holiday Inn Cape Cod - Hyannis (IHG Hotels & Resorts), 3.1 km away
Aiden by Best Western Cape Cod - West Yarmouth (Best Western Hotels & Resorts), 3.4 km away
The Mariner Resort Cape Cod by The Red Collection (Red Roof), 4.0 km away

Frequently asked questions

Where is Comfort Inn Hyannis - Cape Cod?

Comfort Inn Hyannis - Cape Cod is at 259 Main Street, Hyannis, MA, 02601, United States.

Which airport is closest to Comfort Inn Hyannis - Cape Cod?

Cape Cod Gateway Airport (HYA) is the closest airport with scheduled flights, 1.7 km away in a straight line. The drive is longer.

Which hotel group runs Comfort Inn Hyannis - Cape Cod?

Comfort Inn Hyannis - Cape Cod is a Comfort Inn hotel, a brand of Choice Hotels.

All 9 chain hotels in Barnstable

Sources: Choice Hotels's own hotel listing, collected 20 Sep, 2026 via All The Places (CC0); city data from GeoNames; airport positions from OurAirports. FlightGPT does not add details a hotel chain doesn't publish. Rates and availability are checked live when you search.