Hotels in Florence: 12 chain hotels with addresses

12 hotels in Florence, United States from Choice Hotels, Hilton, Marriott International, IHG Hotels & Resorts and more, with addresses, phone numbers and…

FlightGPT lists 12 chain hotels in Florence, United States, from 6 hotel groups: Choice Hotels (4), Hilton (3), Marriott International (2), IHG Hotels & Resorts (1), Red Roof (1), Wyndham Hotels & Resorts (1). For most of them the closest airport is Northwest Alabama Regional Airport (MSL).

Built from each chain's own hotel listing, latest collected 30 Oct, 2026.

Check live hotel rates in Florence

Choice Hotels (4)

Clarion Inn Sheffield Muscle Shoals · 4900 Hatch Boulevard, Sheffield
Comfort Inn & Suites Tuscumbia-Muscle Shoals · 5101 Highway 43 South, Tuscumbia
Comfort Suites Florence Shoals Area · 140 Matthew Paul Court, Florence
Quality Inn Florence East · 150 Etta Gray Drive, Florence

Hilton (3)

Hampton Inn & Suites Florence-Downtown · 505 South Court Street, Florence
Hampton Inn Florence-Midtown · 2281 Florence Blvd., Florence
Spark by Hilton Tuscumbia Muscle Shoals · 712 Hwy 72 West, Tuscumbia

Marriott International (2)

Renaissance Shoals Resort & Spa · 10 Hightower Place, Florence
Residence Inn by Marriott Florence · 1000 Sweetwater Avenue, Florence

IHG Hotels & Resorts (1)

Holiday Inn Express & Suites Florence Northeast · 180 Etta Gray Street, Florence

Red Roof (1)

Red Roof Inn Muscle Shoals · 2807 Woodward Ave, Muscle Shoals

Wyndham Hotels & Resorts (1)

Baymont by Wyndham Florence/Muscle Shoals · 115 Ana Dr, Florence

Frequently asked questions

How many chain hotels are there in Florence?

FlightGPT lists 12 hotels from the large hotel chains in Florence. Independent hotels are not included in this list.

Which hotel groups have hotels in Florence?

Choice Hotels (4), Hilton (3), Marriott International (2), IHG Hotels & Resorts (1), Red Roof (1), Wyndham Hotels & Resorts (1).

Which airport is closest to hotels in Florence?

Northwest Alabama Regional Airport (MSL) is the closest airport with scheduled flights for 11 of the 12 listed hotels.

All cities with chain hotels in United States

Sources: Each chain's own hotel listing, collected 30 Oct, 2026 via All The Places (CC0); city data from GeoNames; airport positions from OurAirports. FlightGPT does not add details a hotel chain doesn't publish. Rates and availability are checked live when you search.