Hotels in Sikeston: 8 chain hotels with addresses

8 hotels in Sikeston, United States from Marriott International, Wyndham Hotels & Resorts, Best Western Hotels & Resorts, Drury Hotels and more, with…

FlightGPT lists 8 chain hotels in Sikeston, United States, from 6 hotel groups: Marriott International (2), Wyndham Hotels & Resorts (2), Best Western Hotels & Resorts (1), Drury Hotels (1), Hilton (1), IHG Hotels & Resorts (1). For most of them the closest airport is Cape Girardeau Regional Airport (CGI).

Built from each chain's own hotel listing, latest collected 30 Oct, 2026.

Check live hotel rates in Sikeston

Marriott International (2)

Fairfield by Marriott Inn & Suites Sikeston · 1239 Commerce Drive, Sikeston
TownePlace Suites by Marriott Sikeston · 1239 Commerce Drive, Sikeston

Wyndham Hotels & Resorts (2)

Days Inn & Suites by Wyndham Sikeston · 220 South Interstate Dr, Sikeston
Super 8 by Wyndham Sikeston/Miner Area · 2609 East Malone, Sikeston

Best Western Hotels & Resorts (1)

Best Western Plus Sikeston · 120 S Interstate Drive, Sikeston

Drury Hotels (1)

Drury Inn & Suites · 2608 East Malone Ave, Sikeston

Hilton (1)

Hampton Inn Sikeston · 1240 Commerce Drive, Sikeston

IHG Hotels & Resorts (1)

Holiday Inn Express & Suites Sikeston · 115 Hospitality Drive, Sikeston

Frequently asked questions

How many chain hotels are there in Sikeston?

FlightGPT lists 8 hotels from the large hotel chains in Sikeston. Independent hotels are not included in this list.

Which hotel groups have hotels in Sikeston?

Marriott International (2), Wyndham Hotels & Resorts (2), Best Western Hotels & Resorts (1), Drury Hotels (1), Hilton (1), IHG Hotels & Resorts (1).

Which airport is closest to hotels in Sikeston?

Cape Girardeau Regional Airport (CGI) is the closest airport with scheduled flights for 6 of the 8 listed hotels.

All cities with chain hotels in United States

Sources: Each chain's own hotel listing, collected 30 Oct, 2026 via All The Places (CC0); city data from GeoNames; airport positions from OurAirports. FlightGPT does not add details a hotel chain doesn't publish. Rates and availability are checked live when you search.