Best Western Plus Sikeston: address, phone and airport distance

Best Western Plus Sikeston, a Best Western Plus hotel (Best Western Hotels & Resorts) in Sikeston, United States.

Best Western Plus Sikeston is a Best Western Plus hotel (Best Western Hotels & Resorts) at 120 S Interstate Drive, Sikeston, MO, 63801-8641, United States. The nearest airport with scheduled flights is Cape Girardeau Regional Airport (CGI), 37.3 km away in a straight line.

From Best Western Hotels & Resorts's own hotel listing, collected 17 Oct, 2026.

Best Western Plus Sikeston: quick facts

Brand: Best Western Plus (Best Western Hotels & Resorts)
Address: 120 S Interstate Drive, Sikeston, MO, 63801-8641
City: Sikeston, Missouri, United States
Phone: +1 573-481-9500
Official hotel page: bestwestern.com
Map: 36.89164, -89.53068

Check live rates for Best Western Plus Sikeston

Nearest airports

Airport	Straight-line distance
Cape Girardeau Regional Airport (CGI)	37.3 km
Barkley Regional Airport (PAH)	69.8 km
Veterans Airport of Southern Illinois (MWA)	105.8 km

Calculated from map positions; the road route is longer.

Hotels from other chains nearby

Drury Inn & Suites (Drury Hotels), 490 m away

Frequently asked questions

Where is Best Western Plus Sikeston?

Best Western Plus Sikeston is at 120 S Interstate Drive, Sikeston, MO, 63801-8641, United States.

Which airport is closest to Best Western Plus Sikeston?

Cape Girardeau Regional Airport (CGI) is the closest airport with scheduled flights, 37.3 km away in a straight line. The drive is longer.

Which hotel group runs Best Western Plus Sikeston?

Best Western Plus Sikeston is a Best Western Plus hotel, a brand of Best Western Hotels & Resorts.

What is the phone number of Best Western Plus Sikeston?

Best Western Hotels & Resorts lists +1 573-481-9500 for Best Western Plus Sikeston.

All 8 chain hotels in Sikeston

Sources: Best Western Hotels & Resorts's own hotel listing, collected 17 Oct, 2026 via All The Places (CC0); city data from GeoNames; airport positions from OurAirports. FlightGPT does not add details a hotel chain doesn't publish. Rates and availability are checked live when you search.