Holiday Inn Express & Suites St. Louis South - I-55: address, phone and airport distance

Holiday Inn Express & Suites St. Louis South - I-55, a Holiday Inn Express hotel (IHG Hotels & Resorts) in St. Louis, United States.

Holiday Inn Express & Suites St. Louis South - I-55 is a Holiday Inn Express hotel (IHG Hotels & Resorts) at 4250 Midamerica Lane, St. Louis, MO, 63129, United States. The nearest airport with scheduled flights is St. Louis Lambert International Airport (STL), 29.3 km away in a straight line.

From IHG Hotels & Resorts's own hotel listing, collected 11 Oct, 2026.

Holiday Inn Express & Suites St. Louis South - I-55: quick facts

Brand: Holiday Inn Express (IHG Hotels & Resorts)
Address: 4250 Midamerica Lane, St. Louis, MO, 63129
City: St. Louis, Missouri, United States
Phone: +1 314-894-0700
Official hotel page: ihg.com
Map: 38.48557, -90.35393

Check live rates for Holiday Inn Express & Suites St. Louis South - I-55

Nearest airports

Airport	Straight-line distance
St. Louis Lambert International Airport (STL)	29.3 km
Scott AFB/Midamerica Airport (BLV)	45.6 km
Veterans Airport of Southern Illinois (MWA)	142.7 km

Calculated from map positions; the road route is longer.

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Hotel Indigo St Louis - Central West End
Hotel Indigo St. Louis - Downtown

Hotels from other chains nearby

Hampton Inn & Suites St. Louis/South I-55 (Hilton), 170 m away
Fairfield by Marriott Inn & Suites St. Louis South (Marriott International), 348 m away
Best Western St. Louis Inn (Best Western Hotels & Resorts), 3.0 km away
Americas Best Value Inn St. Louis South (Sonesta), 3.1 km away
Drury Inn & Suites (Drury Hotels), 5.0 km away

Frequently asked questions

Where is Holiday Inn Express & Suites St. Louis South - I-55?

Holiday Inn Express & Suites St. Louis South - I-55 is at 4250 Midamerica Lane, St. Louis, MO, 63129, United States.

Which airport is closest to Holiday Inn Express & Suites St. Louis South - I-55?

St. Louis Lambert International Airport (STL) is the closest airport with scheduled flights, 29.3 km away in a straight line. The drive is longer.

Which hotel group runs Holiday Inn Express & Suites St. Louis South - I-55?

Holiday Inn Express & Suites St. Louis South - I-55 is a Holiday Inn Express hotel, a brand of IHG Hotels & Resorts.

What is the phone number of Holiday Inn Express & Suites St. Louis South - I-55?

IHG Hotels & Resorts lists +1 314-894-0700 for Holiday Inn Express & Suites St. Louis South - I-55.

All 86 chain hotels in St. Louis

Sources: IHG Hotels & Resorts's own hotel listing, collected 11 Oct, 2026 via All The Places (CC0); city data from GeoNames; airport positions from OurAirports. FlightGPT does not add details a hotel chain doesn't publish. Rates and availability are checked live when you search.